Being out of a job can erode people's confidence and their sense of possibility; and employers, often unfairly, tend to take long-term unemployment as a signal that something is wrong.
I've never understood why the end of a relationship - especially one involving children - has to immediately signal a descent into hatred and toxicity.
We know what molecules are needed to sense light - what turns that signal that detects light into an electrical signal. We know how smells are detected. But we have a vast number of senses for which we know what the signal is, but we don't know what the receiver is.
That would be such a life-changing thing, for us all to know that there are other beings out there who we could potentially communicate with, or maybe we are listening to a signal that they transmitted hundreds of millennia ago.
I studied Latin in high school, and I was reading stuff from Cicero. And that signal took a few thousand years to get to me. But I was still interested in what he had to say.