We lived in a tall, narrow Victorian house, which my parents had bought very cheaply during the war, when everyone thought London was going to be bombed flat. In fact, a V-2 rocket landed a few houses away from ours. I was away with my mother and sister at the time, but my father was in the house.
The radiation left over from the Big Bang is the same as that in your microwave oven but very much less powerful. It would heat your pizza only to minus 271.3*C - not much good for defrosting the pizza, let alone cooking it.
For years, my early work with Roger Penrose seemed to be a disaster for science. It showed that the universe must have begun with a singularity, if Einstein's general theory of relativity is correct. That appeared to indicate that science could not predict how the universe would begin.
It is no good getting furious if you get stuck. What I do is keep thinking about the problem but work on something else. Sometimes it is years before I see the way forward. In the case of information loss and black holes, it was 29 years.
I regard the brain as a computer which will stop working when its components fail. There is no heaven or afterlife for broken down computers; that is a fairy story for people afraid of the dark.
There is a real danger that computers will develop intelligence and take over. We urgently need to develop direct connections to the brain so that computers can add to human intelligence rather than be in opposition.
My advice to other disabled people would be, concentrate on things your disability doesn't prevent you doing well, and don't regret the things it interferes with. Don't be disabled in spirit as well as physically.