Of course there are depressing periods when nothing appears to be happening. But whenever anything was happening, and even when nothing was happening, it was fun just to do phage experiments.
That's the nice thing about doing research. Whatever you do is novel, so you always have this sense of novelty, even if you are only using a new gadget.
When I began playing around at being a physical chemist, I enjoyed very much doing work on the structure of DNA molecules, something which I would never have dreamed of doing before I started.
Year after year, the Nobel Awards bring a moment of happiness not only to the recipients, not only to colleagues and friends of the recipients, but even to strangers.